Restriction of HIV-1 Replication in Monocytes Is Abolished by Vpx of SIVsmmPBj
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چکیده
منابع مشابه
Restriction of HIV-1 Replication in Monocytes Is Abolished by Vpx of SIVsmmPBj
BACKGROUND Human primary monocytes are refractory to infection with the human immunodeficiency virus 1 (HIV-1) or transduction with HIV-1-derived vectors. In contrast, efficient single round transduction of monocytes is mediated by vectors derived from simian immunodeficiency virus of sooty mangabeys (SIVsmmPBj), depending on the presence of the viral accessory protein Vpx. METHODS AND FINDIN...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0007098